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Your Position: Start > Integrin alpha X beta 2

Integrin alpha X beta 2

Brief Information

Name:Integrin alphaxbeta2
Target Synonym:Integrin alphaXbeta2
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:

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IT2-H52W3 Human Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein, His Tag&Tag Free
IT2-H52W3-structure
IT2-H52W3-sds
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Synonym Name

Integrin alpha X beta 2, ITGAX&ITGB2, CD11C, CD18

Background

The integrin αXβ2 takes a key role in host defense and functions as a receptor for the complement C3 cleavage product iC3b, fibrinogen, denatured proteins, and intercellular adhesion molecule (ICAM)-1. Integrin αXβ2 αXβ2 has a unique cellular distribution with expression on monocytes, macrophages, and the CD8− subsets of dendritic cells and involves in priming and regulation of the immune response.

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